Amphetamines

Amphetamines be part of a class of drugs called stimulants that affect the implicit in(p) nervous system. It is also known as 1-methyl-2-phenethylamine, 1-phenyl-2-aminopropane, and Benzedrine. It is made up of a 50/50 mixture of the l and d isomers. The l isomer affects the body, and the d isomer affects the brain. It boils at 200ºC and is dissolvable in alcohol and ether, slightly soluble in water. It was chancellor created in Germany in 1887. In the 1930s and 40s amphetamine was mathematical function in the treatment of asthma, depression, obesity, and narcolepsy. Amphetamines chemical structure is very resembling to the neurotransmitter Adrenaline. chemic structure of Amphetamine, C H CH CH(NH ) CH Method of Preparation there are many ways of creating amphetamines. unity way is to translate two mols, for example, 270 grams, of racemic amphetamine base to play off with ane mol (150 grams) of d-tartaric hot, forming a dl-amphetamine d-tartrate, or a unb iased salt. The impersonal salt obtained is dissolved by the addition of nearly 1 litre, of ethanol, and heating to boiling point. The solution then must(prenominal) be cooled to means temperature with occasional stirring to effect crystallisation. The crystals are filtered out and provide be found to contain laevo enantiomorph, which is the left wing of a pair of crystals that are a mirror regard of each other.

It is then recrystallised and the predominance of the l-enantiomorph is found to be change order and the process is repeated until no further change is unadulterated and a concentration of 8 grams per 100 cc of aqueous s olution is obtained. Finally the product obt! ained is l-amphetamine d-tartrate. d-amphetamine may be convalesce from this by the addition of tartaric bitter for the formation of acid tartrates and separation of d-amphetamine d-bitartrate by crystallisation. Properties and Chemical Reactions of Amphetamines Amphetamines vary... If you want to get a full essay, order it on our website: BestEssayCheap.com

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